Journal of Liver Cancer

Young-Hwa Chung

1 Article

A Case of Advanced Hepatocellular Carcinoma Presenting as Skull Metastasis: Nae-Yun Heo, Han Chu Lee, Ju Hyun Shim, Young-Suk Lim, Young-Hwa Chung, Yung Sang Lee, Dong Jin Suh; Journal of the Korean Liver Cancer Study Group. 2010;10(1):73-75. Published online June 30, 2010

Abstract PDF: Hepatocellular carcinoma is known to spread to distant organ via hematogenous or osseous route in about 15% of the patients during its clinical course. However, it is rare that the distant metastatic symptom and sign are the diagnostic clues to find the primary hepatocellular carcinoma, because most of the patients are likely to expire due to rapid disease progression before the presentation of the clinical findings of metastasis. Detection of early hepatocelluar carcinoma through surveillance of the high risk population will reduce the chance of initial presentation of metastatic symptom. In spite of this trend, we experienced a case of hepatocellular carcinoma presenting as skull metastasis at diagnosis, which suggests that some patients still complain of metastatic symptom as initial presentation of hepatocellular carcinoma.